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Invitrogen™ MYOZ2 Polyclonal Antibody

Product Code. 16508341
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16508341 100 μL 100µL
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Product Code. 16508341 Supplier Invitrogen™ Supplier No. PA592998

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLSHNTMMKQ RKQQATAIMK EVHGNDVDGM DLGKKVSIPR DIMLEELSHL SNRGARLFKM RQRRSDKYTF ENFQYQSRAQ INHSIAMQNG KVDGSNLEGG SQQAPLTPPN TPDPRSPPNP DNIAPGYSGP LKEIPPEKFN TTAVPKYYQS PWEQAISNDP ELLEALYPKL FKPEGKAELP DYRSFNRVAT PFGGFEKASR MVKFKVPDFE LLLLTDPRFM SFVNPLSGRR SFNRTPKGWI SENIPIVITT EPTDDTTVPE SEDL; Positive Samples: Mouse heart, Mouse skeletal muscle, Rat skeletal muscle; Cellular Location: Cytoplasm, Z line, myofibril, sarcomere.

The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOZ2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MYOZ2
Gene Accession No. Q9JJW5, Q9NPC6
Gene Alias 1110012I24Rik; C4orf5; calcineurin-binding protein calsarcin-1; calsarcin-1; CMH16; CS-1; Fatz-2; FATZ-related protein 2; muscle-specific protein; myoz2; myozenin 2; myozenin-2; myozenin-like 2; Myozl2
Gene Symbols MYOZ2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human MYOZ2 (NP_0576831).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 295426, 51778, 59006
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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