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Invitrogen™ MLK4 Polyclonal Antibody
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Product Code. 15632965
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Quantity:
400 μL
Unit Size:
400µL
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15632965 400 μL 400µL
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Product Code. 15632965 Supplier Invitrogen™ Supplier No. PA548666

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Description

Rabbit Polyclonal Antibody

MLK4 Polyclonal Antibody for Western Blot, IHC (P)

MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in kidney and pancreas. MLK4 is a negative regulator of TLR4 and does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLK4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene MAP3K21
Gene Accession No. Q8VDG6
Gene Alias BC021891; cDNA sequence BC021891; dJ862P8.3; Kiaa1804; MAP3K21; Mitogen-activated protein kinase kinase kinase 21; Mitogen-activated protein kinase kinase kinase MLK4; mixed lineage kinase 4; mKIAA1804; MLK4; RGD1306091; similar to Mixed lineage kinase 4
Gene Symbols MAP3K21
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 566-593 amino acids from the Central region of mouse Mlk4.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234878
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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