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MK-886, MedChemExpress

Product Code. 16438597
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Product Code. 16438597

Brand: Medchem Express HY14166

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Description

MedChemExpress MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.

MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.

Specifications

Chemical Name or Material MK-886
CAS 118414-82-7
Color White
Purity Grade Notes Research
Molecular Formula C27H34ClNO2S
Quantity 5 mg
Synonym L 663536
Solubility Information DMSO : 75 mg/mL (158.87 mM; Need ultrasonic)
SMILES CC(C)C1=CC=C(N(CC2=CC=C(Cl)C=C2)C(CC(C)(C(O)=O)C)=C3SC(C)(C)C)C3=C1
Molecular Weight (g/mol) 472.08
Formula Weight 472.08
Percent Purity 99.11%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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