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Masitinib mesylate, MedChemExpress
MedChemExpress Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity.
83.70 EUR - 402.30 EUR
Specifications
| Chemical Name or Material | Masitinib mesylate |
|---|---|
| CAS | 1048007-93-7 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C29H34N6O4S2 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16470097
|
Medchem Express
HY-10209A |
50 mg |
151.20 EUR
50mg |
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|
16444786
|
Medchem Express
HY-10209A |
100 mg |
251.10 EUR
100mg |
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|
16403718
|
Medchem Express
HY-10209A |
10 mg |
83.70 EUR
10mg |
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|
16400956
|
Medchem Express
HY-10209A |
200 mg |
402.30 EUR
200mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity.Specifications
| Masitinib mesylate | |
| White | |
| C29H34N6O4S2 | |
| DMSO : ≥ 30 mg/mL (50.44 mM) | |
| 594.75 | |
| 99.76% | |
| Solid |
| 1048007-93-7 | |
| Research | |
| AB-1010 mesylate | |
| O=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4.CS(=O)(O)=O | |
| 594.75 | |
| Research | |
| Cancer-Kinase/protease |
Safety and Handling
missing translation for 'shelfLife' : 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Recommended Storage : 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Research purposes only
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