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Macozinone, MedChemExpress

Product Code. 16465438
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Product Code. 16465438

Brand: Medchem Express HY12903

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Description

MedChemExpress Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect.

Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect.

Specifications

Chemical Name or Material Macozinone
Physical Form Solid
CAS 1377239-83-2
Color Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C20H23F3N4O3S
For Use With (Application) Cancer-programmed cell death
Synonym PBTZ169
Solubility Information DMSO : 6.4 mg/mL (14.02 mM; Need ultrasonic)
SMILES O=C1C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2SC(N3CCN(CC4CCCCC4)CC3)=N1
Molecular Weight (g/mol) 456.48
Formula Weight 456.48
Percent Purity 99.68%
Grade Research
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Research purposes only

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