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M-110, MedChemExpress

Product Code. 16465378
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Product Code. 16465378 Supplier Medchem Express Supplier No. HY12830

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Description

MedChemExpress M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.

M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC50=47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.

Specifications

Chemical Name or Material M-110
CAS 1395048-49-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H28ClN5O3
Quantity 10 mg
Solubility Information DMSO : 33.33 mg/mL (74.74 mM; Need ultrasonic)
SMILES O=C(N/N=C(C1=CC=C(Cl)C=C1O)\CC)C2=CC(NCCCN3CCOCC3)=NC=C2
Molecular Weight (g/mol) 445.94
Formula Weight 445.94
Percent Purity 95.27%
Grade Research
Physical Form Powder
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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