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Tocris Bioscience™ LY 2389575 hydrochloride
Selective negative allosteric modulator of mGlu3
Brand: Tocris Bioscience™ 4969/10
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Description
LY 2389575 hydrochloride is a selective negative allosteric modulator of mGlu3 (IC50 = 190 nM). Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.Specifications
| >98% | |
| 10 mg |
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