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LIN7C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16883404 Shop All Proteintech Products
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16883404 20 μL 20µL
16873404 150 μL 150µL
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Product Code. 16883404 Supplier Proteintech Supplier No. 146561AP20UL

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Rabbit Polyclonal Antibody

Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.

Specifications

Antigen LIN7C
Applications Western Blot, Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LIN7C
Gene Accession No. O88952, Q792I0, Q9NUP9
Gene Alias LIN 7 C, lin 7 homolog C (C. elegans), LIN 7C, LIN7C, MALS 3, MALS3, Mammalian lin seven protein 3, Protein lin 7 homolog C, Veli 3, VELI3, Vertebrate lin 7 homolog 3
Gene Symbols Lin7c
Host Species Rabbit
Immunogen LIN7C Fusion Protein Ag6265
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22343, 55327, 60442
Target Species Rat, Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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