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Invitrogen™ LEPREL2 Polyclonal Antibody
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Product Code. 16529751
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Quantity:
100 μL
Unit Size:
100µL
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16529751 100 μL 100µL
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Product Code. 16529751 Supplier Invitrogen™ Supplier No. PA596914

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DAAGAGARSG YRGRRSPHTP HERFEGLTVL KAAQLARAGT VGSQGAKLLL EVSERVRTLT QAYFSPERPL HLSFTHLVCR SAIEGEQEQR MDLSHPVHAD NCVLDPDTGE CWREPPAYTY RDYSGLLYLN DDFQGGDLFF TEPNALTVTA RVRPRCGRLV AFSSGVENPH GVWAVTRGRR CALALWHTWA PEHREQEWIE AKELLQESQE EEEEEEEEMP SKDPSPEPPS RRHQRVQDKT GRAPRVREEL; Positive Samples: 22Rv1, NIH/3T3, Mouse skeletal muscle; Cellular Location: Endoplasmic reticulum.

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LEPREL2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.86 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene P3h3
Gene Accession No. Q8CG70, Q8IVL6
Gene Alias BC016431; gene rich cluster, B; GRCB; HSU47926; leprecan-like 2; leprecan-like protein 2; LEPREL2; P3H3; procollagen-proline 3-dioxygenase; prolyl 3-hydroxylase 3; Protein B
Gene Symbols P3h3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 487-736 of human LEPREL2 (NP_0550772).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10536, 14789
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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