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LDN193189, MedChemExpress

Product Code. 16481217
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Product Code. 16481217 Supplier Medchem Express Supplier No. HY12071

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Description

MedChemExpress LDN193189 (DM-3189) is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50≥500 nM).

LDN193189 (DM-3189) is a selective BMP type I receptor inhibitor, which efficiently inhibits ALK2 and ALK3 (IC50=5 nM and 30 nM, respectively), with weaker effects on ALK4, ALK5 and ALK7 (IC50≥500 nM).

Specifications

Chemical Name or Material LDN193189
CAS 1062368-24-4
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C25H22N6
Quantity 50 mg
Synonym DM-3189
Solubility Information DMSO : 12 mg/mL (29.52 mM; ultrasonic and adjust pH to 2 with HCl) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16
Molecular Weight (g/mol) 406.48
Formula Weight 406.48
Percent Purity 98.9%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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