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Larotrectinib, MedChemExpress

Product Code. 16485408
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Product Code. 16485408

Brand: Medchem Express HY12866

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Description

MedChemExpress Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).

Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).

Specifications

Chemical Name or Material Larotrectinib
CAS 1223403-58-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C21H22F2N6O2
Quantity 10 mg
Synonym LOXO-101 ARRY-470
Solubility Information DMSO : ≥ 4.6 mg/mL (10.74 mM)
SMILES O=C(N1C[C@@H](O)CC1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2
Molecular Weight (g/mol) 428.44
Formula Weight 428.44
Percent Purity 98.92%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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