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Lamin A/C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16846593 Shop All Proteintech Products
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150 μL
Unit Size:
150µL
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16846593 150 μL 150µL
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Product Code. 16846593 Supplier Proteintech Supplier No. 102981AP150UL

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Description

Rabbit Polyclonal Antibody

This antibody can recognize 4 isoforms of Lamin A/C.

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

Specifications

Antigen Lamin A/C
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene LMNA
Gene Accession No. P02545, P48678, P48679
Gene Alias 70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, HGPS, IDC, lamin A, lamin A/C, LDP1, LFP, LGMD1B, LMN1, LMNA, LMNC, Prelamin A/C, PRO1, progerin
Gene Symbols Lmna
Host Species Rabbit
Immunogen Lamin A/C Fusion Protein Ag0408
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16905, 4000, 60374
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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