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Epredia™ Lab Vision™ Nucleophosmin (NPM) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Take advantage of a quality product that delivers accurate results with the Epredia™ Nucleophosmin (NPM) Ab-1, Mouse Monoclonal Antibody.
Brand: Epredia™ MS-1849-P1
This item is not returnable.
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Description
Nucleophosmin (NPM)/B23/numatrin is a phosphoprotein associated with cell nucleoli. Treatment of cells with cytotoxic drugs may make nucleophosmin enter nucleoplasm. It is reported that nucleophosmin shuttles continuously between cytoplasm and nucleoli to carry newly synthesized ribosomal proteins into nucleoli. NPM-ALK is a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in anaplastic large cell lymphoma. In acute promyelocytic leukemia NPM gene is fused to RARalpha gene in (5;17) (q33;q12) transition.Host Species: Mouse
Clone: NA24
Isotype: IgG/κ
Species Reactivity: Human. Others not known.
Epitope: N-terminal
Immunogen: GST fusion protein containing the N-terminal part of nucleophosmin fused to 14aa of ALK protein
Molecular Weight: 38kDa
Positive Control: Tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Note:
USA: RUO; Int'l: RUO
Specifications
| Nucleophosmin (NPM) Ab-1 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 500 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG κ |
| Immunohistochemistry (Paraffin) | |
| NA24 | |
| Unconjugated | |
| GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 aa of ALK protein | |
| RUO | |
| Primary | |
| Concentrated |
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