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  6. KS176, MedChemExpress

KS176, MedChemExpress

Product Code. p-200102125
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Product Code. 16490348

Brand: Medchem Express HY19753

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Description

MedChemExpress KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 (mu)M in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.

KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 (mu)M in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.

Specifications

Chemical Name or Material KS176
Physical Form Solid
CAS 1253452-78-6
Color White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C22H19N3O5
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 35 mg/mL (86.33 mM)
SMILES O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3
Molecular Weight (g/mol) 405.4
Formula Weight 405.4
Percent Purity 98.01%
Grade Research
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Research purposes only

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