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K145 hydrochloride, MedChemExpress

Product Code. 16439377
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Product Code. 16439377

Brand: Medchem Express HY15779A

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MedChemExpress K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.

K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.

Specifications

Chemical Name or Material K145 hydrochloride
CAS 1449240-68-9
Color White
Purity Grade Notes Research
Molecular Formula C18H25ClN2O3S
Quantity 5 mg
Solubility Information H2O : 126.7 mg/mL (329.16 mM; Need ultrasonic and warming) ∣DMSO : 50 mg/mL (129.90 mM; Need ultrasonic)
SMILES O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl
Molecular Weight (g/mol) 384.92
Formula Weight 384.92
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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