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Invitrogen™ K-cadherin Polyclonal Antibody

Description
Immunogen sequence: LDRETLLWHN ITVIATEINN PKQSSRVPLY IKVLDVNDNA PEFAEFYETF VCEKAKADQL IQTLHAVDKD DPYSGHQFSF SLAPEAASGS NFTIQDNKDN TAGILTRKNG YNRHEMSTYL LP Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 98%.
Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.
Specifications
Specifications
| Antigen | K-cadherin |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.10 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CDH6 |
| Gene Accession No. | P55285 |
| Gene Alias | CAD6; CADH6; cadherin 6; cadherin 6, type 2, K-cadherin; cadherin 6, type 2, K-cadherin (fetal kidney); Cadherin6; cadherin-6; Cdh6; k cadherin; KCAD; K-cadherin; Kidney cadherin |
| Gene Symbols | CDH6 |
| Show More |
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