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Invitrogen™ JMJD2B Monoclonal Antibody (3A6H6)

Description
MA5-31784 has been tested in indirect ELISA.
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt].
Specifications
Specifications
| Antigen | JMJD2B |
| Applications | ELISA, Flow Cytometry, Western Blot |
| Classification | Monoclonal |
| Clone | 3A6H6 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% sodium azide |
| Gene | KDM4B |
| Gene Accession No. | O94953, Q91VY5 |
| Gene Alias | 4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B |
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