missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 13268178

Invitrogen™ JMJD1A Polyclonal Antibody
GREENER_CHOICE

Product Code. 13268178
Change view
Click to view available options
Quantity:
100 μL
Unit Size:
100µL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
13268178 100 μL 100µL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 13268178 Supplier Invitrogen™ Supplier No. PA523066

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

The target sequence has 91% sequence homology with rat.

JMJD1A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. JMJD1A is involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. It's also Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD1A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.05% sodium azide
Gene KDM3A
Gene Accession No. Q63679, Q6PCM1, Q9Y4C1
Gene Alias 1700105C21Rik; C230043E16Rik; DKFZp686A24246; DKFZp686P07111; JHDM2a; JHMD2A; JmjC domain-containing histone demethylation protein 2A; Jmjd1; Jmjd1a; jumonji C domain-containing histone demethylase 2A; jumonji domain containing 1A; jumonji domain-containing protein 1A; KDM2A; Kdm3a; Kiaa0742; lysine (K)-specific demethylase 3A; lysine demethylase 3A; lysine-specific demethylase 3A; probable zinc finger protein; testis specific gene A; testis-specific gene A protein; testis-specific protein A; TGSA; Tsga; zinc finger protein TSGA
Gene Symbols KDM3A
Host Species Rabbit
Immunogen A genomic peptide made to an internal region of the human JMJD1A protein (within residues 250-400).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104263, 312440, 55818
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.