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ISRIB (trans-isomer), MedChemExpress

Product Code. 16465208
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Product Code. 16465208 Supplier Medchem Express Supplier No. HY12495

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Description

MedChemExpress ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM).

ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM).

Specifications

Chemical Name or Material ISRIB (trans-isomer)
CAS 1597403-47-8
Color White
Purity Grade Notes Research
Molecular Formula C22H24Cl2N2O4
Quantity 10 mg
Solubility Information DMSO : 4.55 mg/mL (10.08 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C(N[C@H]1CC[C@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3.[Relative stereochemistry]
Molecular Weight (g/mol) 451.34
Formula Weight 451.34
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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