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IGF2BP3 Monoclonal Antibody (OTI6A4), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA811488
This item is not returnable.
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Description
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some maligcies. IMP-3 is expressed in maligt melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of maligt melanoma and may play an important role in the regulation of the biologic behavior of this tumor.Specifications
| IGF2BP3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| O00425 | |
| IGF2BP3 | |
| Full length human recombit protein of human IGF2BP3 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI6A4 | |
| Unconjugated | |
| IGF2BP3 | |
| CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 10643 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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