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Invitrogen™ Human UCP3 (aa 195-222) Control Fragment Recombinant Protein

Product Code. 30203842
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30203842

Brand: Invitrogen™ RP107867

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67230 (PA5-67230. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P55916
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 7352
Name Human UCP3 (aa 195-222) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Common Name UCP3
Gene Symbol Ucp3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence AEVVTYDILKEKLLDYHLLTDNFPCHFV
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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