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Invitrogen™ Human TCEB1 (aa 56-90) Control Fragment Recombinant Protein

Product Code. 30204703
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30204703

Brand: Invitrogen™ RP108139

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67489 (PA5-67489. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q15369
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 6921
Name Human TCEB1 (aa 56-90) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; eloC; elongation factor SIII p15 subunit; elongin 15 kDa subunit; elongin C; elongin-C; RNA polymerase II transcription factor SIII subunit C; SIII; SIII p15; Stromal membrane-associated protein SMAP1B homolog; Tceb1; transcription elongation factor B (SIII), polypeptide 1; transcription elongation factor B (SIII), polypeptide 1 (15 kDa, elongin C); transcription elongation factor B polypeptide 1; transcription elongation factor B polypeptide 1; elongin-C; transcription elongation factor B subunit 1
Common Name TCEB1
Gene Symbol ELOC
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ETNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEI
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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