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Invitrogen™ Human RXRG (aa 179-276) Control Fragment Recombinant Protein

Product Code. 30204295
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30204295

Brand: Invitrogen™ RP108308

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82475 (PA5-82475. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P48443
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 6258
Name Human RXRG (aa 179-276) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias Nr2b3; Nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma; retinoic x receptor gamma-1; retinoid x receptor; retinoid x receptor gamma; retinoid x receptor, gamma; RXR gamma; RXR gamma-1; RXRC; RXRG
Common Name RXRG
Gene Symbol RXRG
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQ
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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