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Invitrogen™ Human PLEKHO1 Synthetic Peptide

Product Code. 15309190
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity unitSize
15309190 50 μg 50µg
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Product Code. 15309190 Supplier Invitrogen™ Supplier No. PEP0941

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Description

Synthetic Peptide

CKIP1 Synthetic Peptide, PEP-0941, from Invitrogen.

CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha', and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 51177
Species Human
Purification Method purified
Accession Number Q53GL0
Common Name Human PLEKHO1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol PLEKHO1
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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