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Invitrogen™ Human KCNJ14 (aa 407-436) Control Fragment Recombinant Protein

Product Code. 30206921
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Quantity:
100 μL
Packungsgröße:
100µL
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30206921 100 μL 100µL
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Artikelnummer. 30206921 Lieferant Invitrogen™ Lieferanten-Nr. RP105545

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Beschreibung

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67198 (PA5-67198. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.
TRUSTED_SUSTAINABILITY

Spezifikation

Accession Number Q9UNX9
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3770
Name Human KCNJ14 (aa 407-436) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias A930026G01Rik; ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel KIR2.4; IRK4; IRK-4; KCNJ14; KIR2.4; potassium channel, inwardly rectifying subfamily J member 14; potassium channel, inwardly rectifying subfamily J, member 14; potassium inwardly-rectifying channel J14; potassium inwardly-rectifying channel, subfamily J, member 14; potassium voltage-gated channel subfamily J member 14
Common Name KCNJ14
Gene Symbol KCNJ14
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ETEEGNGVETEDGAASPRVLTPTLALTLPP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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