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  5. Invitrogen™ Human ILT-2/LIR-1/CD85j ELISA Kit

Invitrogen™ Human ILT-2/LIR-1/CD85j ELISA Kit

Product Code. p-7219470
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Quantity:
5 x 96 Tests
96 Tests
Unit Size:
Each
Pack of 96
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Product Code. 17185039

Brand: Invitrogen™ EH277RBX5

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Description

ELISA

Human ILT-2/LIR-1/CD85j quantitates human ILT-2/LIR-1/CD85j in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ILT-2/LIR-1/CD85j.

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B
Assay Range 22 to 5,000 pg/mL
Assay Sensitivity 22 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 10859
Gene Symbol LILRB1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target CD85j (ILT2)
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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