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Gibco™ Human IL-35 Recombinant Protein, PeproTech®

Product Code. 17880163
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Quantity:
10 μg
10 x 50 μg
2 μg
2 x 50 μg
20 x 50 μg
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50 μg
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1mg
250µg
2µg
500µg
50µg
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Product Code. Quantity unitSize
17880163 10 μg 10µg
17881203 2 x 50 μg 100µg
17821223 20 x 50 μg 1mg
17831313 5 x 50 μg 250µg
17870353 2 μg 2µg
17850233 10 x 50 μg 500µg
17820743 50 μg 50µg
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Product Code. 17880163 Supplier Gibco™ Supplier No. 2003710UG

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Recombinant Protein

200-37-100UG will be provided as 2 x 50 μg (200-37-50UG). 200-37-1MG will be provided as 20 x 50 μg (200-37-50UG). 200-37-250UG will be provided as 5 x 50 μg (200-37-50UG). 200-37-500UG will be provided as 5 x 100 μg (200-37-50UG). Recombinant Recombinant Human IL-35 expressed in HEK293 cells contains 406 amino acid residues and has a calculated molecular weight of 45.8 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

IL-35, or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to induce proliferation of regulatory T cells, and reduce the activity of helper Th17 cells.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P29459
For Use With (Application) Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 3592
Molecular Weight (g/mol) 45.8 kDa
Name Human IL-35
Purification Method Purified
Quantity 10 μg
Source HEK293 cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias CLMF; CLMF p35; cytokine receptor; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; EBI3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; epstein-Barr virus-induced gene 3 protein; IL-12 subunit p35; IL-12, subunit p35; IL12A; IL-12A; IL12p35; IL27 subunit; IL-27 subunit beta; IL27B; IL-27B; il35; IL35 subunit; ILN; Interleukin; interleukin 12, p35; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 alpha chain; interleukin-12 subunit alpha; Interleukin-27 subunit beta; Interleukin-35; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NKSF1; P35
Common Name IL-35
Gene Symbol IL12A
Biological Activity Measured by its ability to inhibit proliferative activity of PBMCs.
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence Alpha Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS Beta Subunit: RKGPPAALTL PRVQCRASRY PIAVDCSWTL PPAPNSTSPV SFIATYRLGM AARGHSWPCL QQTPTSTSCT ITDVQLFSMA PYVLNVTAVH PWGSSSSFVP FITEHIIKPD PPEGVRLSPL AERQLQVQWE PPGSWPFPEI FSLKYWIRYK RQGAARFHRV GPIEATSFIL RAVRPRARYY VQVAAQDLTD YGELSDWSLP ATATMSLGK
Content And Storage -20°C
Activity Measured by its ability to inhibit proliferative activity of PBMCs.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade ≥ 90% by SDS-PAGE gel and HPLC analyses.
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