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Gibco™ Human I-TAC (CXCL11) Recombinant Protein, PeproTech®

Product Code. 17852183
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Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
50 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
50µg
5µg
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Product Code. 17852183

Brand: Gibco™ 30046100UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human I-TAC is an 8.3 kDa protein containing 73 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O14625
For Use With (Application) ELISA, Functional Assay, Western Blot
Formulation protein with no preservative
Gene ID (Entrez) 6373
Molecular Weight (g/mol) 8.3 kDa
Name Human I-TAC (CXCL11)
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias betaR1; beta-R1; b-R1; C Cmotif chemokine; C x C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9 B; small-inducible cytokine B11
Common Name CXCL11
Gene Symbol CXCL11
Biological Activity Determined by its ability to chemoattract IL-2-activated T-cells using a concentration range of 0.1-10.0 ng/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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