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Invitrogen™ Human Flt-3 ELISA Kit
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Quantity:
10 x 96 Tests
5 x 96 Tests
96 Tests
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Each
Pack of 10
Pack of 96
Description
Human Flt-3 quantitates human Flt-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Flt-3.
FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Spécification
Spécification
| Accession Number | B230315G04; CD135; CD135 antigen; fetal liver kinase 2; Fetal liver kinase-2; FL cytokine receptor; Flk2; Flk-2; Flt3; Flt-3; fms related tyrosine kinase 3; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Ly72; OTTHUMP00000214829; Receptor-type tyrosine-protein kinase FLT3; RP11-153M24.3; stem cell tyrosine kinase 1; STK1; STK-1; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmfl |
| Assay Range | 0.246 to 60 ng/mL |
| Assay Sensitivity | 0.24 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Gene ID (Entrez) | 2322 |
| Gene Symbol | FLT3 |
| Interassay CV | <12% |
| Afficher plus |
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