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Gibco™ Human CCL21 (6Ckine) Recombinant Protein, PeproTech®

Product Code. 17882723
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17882723 500 μg 500µg
17832923 100 μg 100µg
17832203 1 mg 1mg
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17892793 250 μg 250µg
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Product Code. 17882723 Supplier Gibco™ Supplier No. 30035A500UG

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Description

Recombinant Protein

Recombinant Human Exodus-2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues. *Human Exodus-2 (Catalog Number 300-35A) has replaced Human Exodus-2 (Catalog Number 300-35). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O00585
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 6366
Molecular Weight (g/mol) 12.2 kDa
Name Human CCL21 (6 Ckine)
Quantity 500 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 6 Ckine; 6 CKBAC1; 6 CKBAC2; 6 Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6 Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21 A; C-C motif chemokine 21 b; C-C motif chemokine 21 c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21 A (serine); chemokine (C-C motif) ligand 21 B (leucine); chemokine (C-C motif) ligand 21 b (serine); chemokine (C-C motif) ligand 21 C (leucine); chemokine CCL21/6 CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600
Common Name CCL21
Gene Symbol CCL21
Biological Activity Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2.
Conjugate Unconjugated
Recombinant Recombinant
Sequence SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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