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Invitrogen™ Human ASCC2 (aa 590-740) Control Fragment Recombinant Protein

Product Code. 30207728
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30207728

Brand: Invitrogen™ RP91350

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51579 (PA5-51579. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H1I8
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 84164
Name Human ASCC2 (aa 590-740) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1700011I11Rik; 2610034L15Rik; activating signal cointegrator 1 complex subunit 2; AI482016; ASC-1 complex subunit P100; Asc1p100; ASCC2; AW046480; p100; RGD1561422; trip4 complex subunit p100
Common Name ASCC2
Gene Symbol ASCC2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence YSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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