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Tocris Bioscience™ HTH 01-015
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Potent and selective NUAK1 inhibitor

Brand:  Tocris Bioscience™ 5622/50

Encompass

Product Code. 15776986

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Description

Description

HTH 01-015 is a potent and selective NUAK1 inhibitor (IC50 = 100 nM). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells in vitro, to a similar extent as NUAK1 knockdown models.
Specifications

Specifications

5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one
1613724-42-7
50 mg
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