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Invitrogen™ HIV1 gp120 Synthetic Peptide
Description
gp120 Synthetic Peptide, PEP-0704, from Invitrogen.
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Specifications
Specifications
| Species | Virus |
| Purification Method | purified |
| Common Name | HIV1 gp120 |
| Concentration | 1 mg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| For Use With (Application) | Blocking Assay, Control |
| Lyophilized | No |
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