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Invitrogen™ HFE Monoclonal Antibody (3F1)

Description
MA5-15907 targets HFE in indirect ELISA, IF and WB applications and shows reactivity with Human samples. The MA5-15907 immunogen is purified recombinant fragment of human HFE expressed in E. Coli. . MA5-15907 detects HFE which has a predicted molecular weight of approximately 40kDa.
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin. It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Specifications
Specifications
| Antigen | HFE |
| Applications | ELISA, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 3F1 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Ascites with 0.03% sodium azide |
| Gene | HFE |
| Gene Accession No. | Q30201 |
| Gene Alias | hemochromatosis; hereditary hemochromatosis protein; hereditary hemochromatosis protein HLA-H; hereditary hemochromatosis protein homolog; Hfe; HFE 1; HFE1; HH; high Fe; HLA H; HLAH; HLA-H; MGC:150812; MGC10379; MGC103790; MHC class I-like protein HFE; Mr2; MVCD7; RT1-CAFE; TFQTL2 |
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