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GW806742X, MedChemExpress
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Quantity:
5 mg
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
5mg
Description
GW806742X, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 μM. GW806742X has activity against VEGFR2 (IC50=2 nM). GW806742X retards MLKL membrane translocation and inhibits necroptosis.
Specifications
Specifications
| Chemical Name or Material | GW806742X |
| CAS | 579515-63-2 |
| Color | Off-White |
| Purity Grade Notes | Research |
| Molecular Formula | C25H22F3N7O4S |
| Quantity | 5 mg |
| Solubility Information | DMSO : 100 mg/mL (174.35 mM; Need ultrasonic) |
| SMILES | O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O |
| Molecular Weight (g/mol) | 573.55 |
| Formula Weight | 573.55 |
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Research purposes only
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