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GRB10 Monoclonal Antibody (OTI5A6), TrueMAB™, OriGene

Product Code. 17556764
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100 μL
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17556764 100 μL 100µL
17576764 30 μL 30µL
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Product Code. 17556764 Supplier Origene Technologies Supplier No. TA812343

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Description

Mouse Monoclonal Antibody

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

Specifications

Antigen GRB10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI5A6
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene GRB10
Gene Accession No. Q13322
Gene Alias GRB-IR, Grb-10, IRBP, MEG1, RSS
Gene Symbols GRB10
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 164-415 of human GRB10 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2887
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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