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Grazoprevir, MedChemExpress

Product Code. 16496716
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Product Code. 16496716 Supplier Medchem Express Supplier No. HY15298

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Description

MedChemExpress Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir inhibits SARS-CoV-2 3CLpro activity.

Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir inhibits SARS-CoV-2 3CLpro activity.

Specifications

Chemical Name or Material Grazoprevir
CAS 1350514-68-9
Color White
Purity Grade Notes Research
Molecular Formula C38H50N6O9S
Quantity 100 mg
Synonym MK-5172
Solubility Information DMSO : 50 mg/mL (65.20 mM; Need ultrasonic)
SMILES COC1=CC2=C(N=C(CCCCC[C@@H]3C[C@H]3OC4=O)C(O[C@H]5CN(C([C@H](C(C)(C)C)N4)=O)[C@H](C(N[C@@]([C@@H]6C=C)(C6)C(NS(C7CC7)(=O)=O)=O)=O)C5)=N2)C=C1
Molecular Weight (g/mol) 766.9
Formula Weight 766.9
Percent Purity 99.14%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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