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Grazoprevir hydrate, MedChemExpress

Product Code. p-200101711
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Product Code. 16472537 Supplier Medchem Express Supplier No. HY15298B

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Description

MedChemExpress Grazoprevir hydrate (MK-5172 hydrate) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir hydrate inhibits SARS-CoV-2 3CLpro activity.

Grazoprevir hydrate (MK-5172 hydrate) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir hydrate inhibits SARS-CoV-2 3CLpro activity.

Specifications

Chemical Name or Material Grazoprevir hydrate
CAS 1350462-55-3
Color White
Purity Grade Notes Research
Molecular Formula C38H52N6O10S
Quantity 50 mg
Synonym MK-5172 hydrate
Solubility Information DMSO : 50 mg/mL (63.70 mM; Need ultrasonic)
SMILES COC1=CC2=C(N=C(CCCCC[C@@H]3C[C@H]3OC4=O)C(O[C@H]5CN(C([C@H](C(C)(C)C)N4)=O)[C@H](C(N[C@@]([C@@H]6C=C)(C6)C(NS(C7CC7)(=O)=O)=O)=O)C5)=N2)C=C1.O
Molecular Weight (g/mol) 784.92
Formula Weight 784.92
Percent Purity 99.1%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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