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Invitrogen™ GPR77 Polyclonal Antibody
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Product Code. 13474509
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity unitSize
13474509 50 μg 50µg
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Product Code. 13474509 Supplier Invitrogen™ Supplier No. PA532840

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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon (95%); Monkey (85%); Marmoset (80%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR77
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene C5AR2
Gene Accession No. Q9P296
Gene Alias C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5AR2; C5L2; Complement component 5a receptor 2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; GPF77; GPR77; G-protein coupled receptor 77
Gene Symbols C5AR2
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from N-terminal extracellular domain of human C5L2.
Purification Method Antigen Affinity Chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27202
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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