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Gibco™ Human IL-2 Recombinant Protein

Product Code. 10777863
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Quantity:
1 mg
10 μg
100 μg
40 μg
Unit Size:
40µg
Each
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Product Code. 10777863

Brand: Gibco™ PHC0027

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This item is not returnable. View return policy

Description

Recombinant Protein

Carrier-Free Reconstitution: Centrifuge the vial briefly, before opening to bring the contents to the bottom. Reconstitute the lyophilized protein in100 mM acetic acid to 0.1-1.0 mg/mL to regain full activity. Make any further dilutions of the reconstituted protein in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA. Storage: Store the lyophilized protein at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤-20°C (not in a frost-free freezer). Avoid repeated freeze-thaw cycles.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P60568
For Use With (Application) Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 3558
Molecular Weight (g/mol) 15.5 kDa
Name Human IL-2
Purification Method Purified
Quantity 40 μg
Storage Requirements 4°C
Regulatory Status RUO
Endotoxin Concentration <0.1 ng/μg
Gene Alias aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Common Name IL-2
Gene Symbol IL2
Biological Activity ED50 < 0.5 ng/mL; determined by the dose-dependen proliferation of mouse CTLL-2 cells.
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Content And Storage 4°C
Classification Carrier-Free
Activity ED50 < 0.5 ng/mL; determined by the dose-dependen proliferation of mouse CTLL-2 cells.
Endotoxin Level <0.1 ng/μg
Shipping Condition Wet Ice
Expression System E. coli
Protein Family Cytokines & Receptors
Protein Form Recombinant, Ligand, Mutant
Form Lyophilized
Protein Subtype Interleukins
Research Category Immunology, Signal Transduction, Stem Cell Research, Angiogenesis, Oncology
Product Line Gibco
Purity or Quality Grade >95% by SDS-PAGE
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