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Thermo Scientific™ GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Cells
Description
GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells contain the human KiSS1 receptor (GPR54) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line. CellSensor™ NFAT-bla CHO-K1 cells (Cat. No. K1534) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.
The GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of Metastin. In addition, GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
The GPR54 receptor has been shown to be involved in tumor progression and metastasis, and in the development and functional regulation of the gonads.
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Specifications
Specifications
| Accession Number | NP_115940.1 |
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells • GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis The GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
| Description | GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Cells, 2 x 106 Cells, ∽2,600,000 cells/vial at 2,600,000 cells/mL Quantity of Cells, CHO-K1 Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage |
| Detection Method | Fluorescence |
| For Use With (Application) | FRET |
| Gene Symbol | GPR54 |
| Includes | GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: GeneBLAzer™ GPR54-NFAT-bla CHO-K1 cells, GeneBLAzer™ GPR54-NFAT-bla CHO-K1 Assay Protocol, Certificate of Analysis |
| Population Status | Single Cell Clone Origin |
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For Research Use Only. Not for use in diagnostic procedures.
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