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G-749, MedChemExpress

Product Code. 16497817
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Product Code. 16497817

Brand: Medchem Express HY12333

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Description

MedChemExpress G-749 is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. G-749 can be used for the research of drug resistance for acute myeloid leukemia (AML).

G-749 is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. G-749 can be used for the research of drug resistance for acute myeloid leukemia (AML).

Specifications

Chemical Name or Material G-749
CAS 1457983-28-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C25H25BrN6O2
Quantity 5 mg
Solubility Information DMSO : 25 mg/mL (47.95 mM; Need ultrasonic)
SMILES O=C1C2=C(N=C(NC3CCN(C)CC3)N=C2NC4=CC=C(OC5=CC=CC=C5)C=C4)C(Br)=CN1
Molecular Weight (g/mol) 521.41
Formula Weight 521.41
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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