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FX-11, MedChemExpress

Product Code. 16489547
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Product Code. 16489547 Supplier Medchem Express Supplier No. HY16214

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Description

MedChemExpress FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) specific inhibitor, with a Ki of 8 μM. FX-11 can effectively activate PKM2 (pyruvate kinase M2). FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts.

FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) specific inhibitor, with a Ki of 8 μM. FX-11 can effectively activate PKM2 (pyruvate kinase M2). FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts.

Specifications

Chemical Name or Material FX-11
CAS 213971-34-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C22H22O4
Quantity 5 mg
Synonym LDHA Inhibitor FX11
Solubility Information DMSO : 250 mg/mL (713.45 mM; Need ultrasonic)
SMILES O=C(C1=C2C=C(CC3=CC=CC=C3)C(C)=CC2=C(CCC)C(O)=C1O)O
Molecular Weight (g/mol) 350.41
Formula Weight 350.41
Percent Purity 98.44%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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