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  6. FR4 Monoclonal Antibody (eBioTH6), Functional Grade, eBioscience™, Invitrogen™

FR4 Monoclonal Antibody (eBioTH6), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

8960.00 EUR - 14910.00 EUR

Specifications

Antigen FR4
Clone eBioTH6
Concentration 1 mg/mL
Applications Flow Cytometry, Functional Assay, Immunoprecipitation
Classification Monoclonal
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Description

Description

The MAb eBioTh6 recognizes FR4, also known as FR delta and FBP3 (folate binding protein3). FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors. Based on co-staining studies, the epitopes recognized by eBioTH6 and eBio12A5 (cat 51-5445) are different thereby allowing functional studies with TH6 to be evaluated with eBio12A5.

FR4 Monoclonal antibody specifically detects FR4 in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunoprecipitation
Specifications

Specifications

FR4
1 mg/mL
Monoclonal
Liquid
RUO
PBS with no preservative; pH 7.2
0910001L11Rik; C86255; Folate receptor 4; folate receptor 4 (delta); folate receptor 4 (delta) homolog; folate receptor 4, delta (putative); Folate receptor delta; folate-binding protein 3; Folbp3; FOLR4; FR-delta; IZUMO1 receptor protein JUNO; IZUMO1 receptor, JUNO; Izumo1r; Juno; probable folate receptor delta; sperm-egg fusion protein Juno
IgG2b κ
Affinity chromatography
Antibody
eBioTH6
Flow Cytometry, Functional Assay, Immunoprecipitation
Functional Grade
Rat
Mouse
Q9EQF4
64931
Primary
4° C
Izumo1r
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SDS
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Documents

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