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  8. Fostamatinib Disodium, MedChemExpress

Fostamatinib Disodium, MedChemExpress

Product Code. p-200096271
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Product Code. 16498217

Brand: Medchem Express HY13038

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Description

MedChemExpress Fostamatinib Disodium (R788 Disodium) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Fostamatinib Disodium (R788 Disodium) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Specifications

Chemical Name or Material Fostamatinib Disodium
CAS 1025687-58-4
Color White
Purity Grade Notes Research
Molecular Formula C23H24FN6Na2O9P
Quantity 5 mg
Synonym R788(Disodium)
Solubility Information DMSO : 50 mg/mL (80.07 mM; Need ultrasonic)
SMILES COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC
Molecular Weight (g/mol) 624.42
Formula Weight 624.42
Percent Purity 98.94%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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