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  8. Fostamatinib disodium hexahydrate, MedChemExpress

Fostamatinib disodium hexahydrate, MedChemExpress

Product Code. 16476086
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Product Code. 16476086 Supplier Medchem Express Supplier No. HY13038B

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Description

MedChemExpress Fostamatinib (R788) disodium hexahydrate is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Fostamatinib (R788) disodium hexahydrate is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).

Specifications

Chemical Name or Material Fostamatinib disodium hexahydrate
CAS 914295-16-2
Color White
Purity Grade Notes Research
Molecular Formula C23H36FN6Na2O15P
Quantity 100 mg
Synonym R788 disodium hexahydrate
Solubility Information DMSO : 31.81 mg/mL (43.43 mM; Need ultrasonic) ∣H2O : 2 mg/mL (2.73 mM; ultrasonic and warming and heat to 60°C)
SMILES COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC.O.O.O.O.O.O
Molecular Weight (g/mol) 732.51
Formula Weight 732.51
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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