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Forodesine, MedChemExpress

Product Code. 16479547
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5 mg
Unit Size:
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Product Code. 16479547 Supplier Medchem Express Supplier No. HY16210

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Description

MedChemExpress Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels.

Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels.

Specifications

Chemical Name or Material Forodesine
CAS 209799-67-7
Color Gray
Purity Grade Notes Research
Molecular Formula C11H14N4O4
Quantity 5 mg
Synonym BCX-1777 Immucillin-H
SMILES O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1
Molecular Weight (g/mol) 266.25
Formula Weight 266.25
Percent Purity 97.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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