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Invitrogen™ FAM65A Polyclonal Antibody

Description
Immunogen sequence: LSLRQPGLAE AVCVKFLEDA LGQKLPRRPQ PGPGEQLTVF QFWSFVETLD SPTMEAYVTE TAEEVLLVRN LNSDDQAVVL KALRLAPEGR LRRDGLRALS SLLVHGNNKV MAAVSTQLRS LSLGPTFRER ALLCFLDQLE DEDVQTRVAG CLALGCIKAP EGIEPLVYLC QTDTEAVREA ARQSLQQCGE EGQSAHRRLE ESLDALPRIF GPGSMASTAF; Positive Samples: Mouse kidney; Cellular Location: Cytoplasm.
Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt].
Specifications
Specifications
| Antigen | FAM65A |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.7 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 |
| Gene | RIPOR1 |
| Gene Accession No. | Q68FE6 |
| Gene Alias | 2310066E14Rik; AI837433; Fam65a; family with sequence similarity 65 member A; family with sequence similarity 65, member A; FLJ13725; Kiaa1930; protein FAM65A; Rho family-interacting cell polarization regulator 1; RIPOR1 |
| Gene Symbols | RIPOR1 |
| Show More |
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