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Invitrogen™ ErbB2 (HER-2) Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA516305
This item is not returnable.
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Description
PA5-16305 targets HER-2 in IHC (P), IP, and WB applications and shows reactivity with mouse, Non-human primate, Rat, and Human samples. The PA5-16305 immunogen is synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein.
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
Specifications
| ErbB2 (HER-2) | |
| Polyclonal | |
| Unconjugated | |
| ERBB2 | |
| avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | |
| Rabbit | |
| Protein A | |
| RUO | |
| 13866, 2064, 24337 | |
| 4°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P04626, P06494, P70424 | |
| ERBB2 | |
| Synthetic peptide derived from C-terminus of human c-erbB-2/HER-2 protein. This Sequence is identical in rat neu protein. | |
| 500 μL | |
| Primary | |
| Human, Mouse, Rat, Monkey | |
| Antibody | |
| IgG |
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