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Invitrogen™ EPS8L1 Polyclonal Antibody
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Product Code. 16667694
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Quantity:
100 μL
Unit Size:
100µL
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16667694 100 μL 100µL
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Product Code. 16667694 Supplier Invitrogen™ Supplier No. PA5101217

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ES8L1.

Eps8L1 (EPS8-like 1), also known as DRC3 or EPS8R1, is a 723 amino acid protein that localizes to the cytoplasm and belongs to the Eps8 (epidermal growth factor receptor pathway substrate 8) family. Expressed in placental tissue, Eps8L1 functions to stimulate the guanine exchange activity of Sos 1 (son of sevenless homolog 1), a protein that promotes the exchange of Ras-bound GDP for GTP. Additionally, Eps8L1 is thought to associate with Actin and, via this association, may play a role in membrane ruffling and remodeling of the Actin cytoskeleton. Through its ability to regulate protein activation and cytoskeleton dynamics, Eps8L1 may participate in cell growth and differentiation events within the cell. Eps8L1 contains one SH3 domain and is expressed as four isoforms due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EPS8L1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EPS8L1
Gene Accession No. Q8R5F8, Q8TE68
Gene Alias 2310051G19Rik; 4632407K17Rik; AW060268; DRC3; Epidermal growth factor receptor kinase substrate 8-like protein 1; epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8 like 1; Eps8l1; EPS8-like 1; EPS8-like protein 1; Eps8r1; EPS8-related protein 1; PP10566
Gene Symbols EPS8L1
Host Species Rabbit
Immunogen A synthesized peptide derived from human EPS8L1(Accession Q8TE68), corresponding to amino acid residues Y416-L466.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54869, 67425
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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